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David Sinclairs Complete Supplement List in 2025 Nicotinamide Mononucleotide (NMN): 1 gram daily Resveratrol: 1 gram daily with yogurt Spermidine: 1-2 mg daily Fisetin: 500 mg daily Vitamin D3: 4,000-5,000 IU daily Vitamin K2: 180-360 mcg daily Trimethylglycine (TMG/Betaine): 500-1,000 mg daily Omega-3 Fish Oil: Dosage not specified L-Taurine: 2 grams daily CoQ10: Dosage not specified in recent sources Metformin: 800-1,000 mg in the evening Low-Dose Aspirin: 83 mg daily Rapamycin: Dosage not publicly disclosed The sections that follow will explore each supplement in detail, covering how they work, the evidence behind them, and practical considerations for anyone interested in longevity

Vitamin D contributes to the normal function of the immune system

[DOI] [PubMed] [PMC] Mohammadi-Nejad AR, Craig M, Cox E, Chen X, Jenkins RG, Francis S, et al

Bypassing the digestive system is the main advantage of our Vitamin IV Infusions

Optic Labs supplies BAC water as a sterile clear liquid in sealed multi-dose research vials at 3ml and 10ml fill volumes